| Brothers (2024)As Cath | (Not seen) |
| The Deliverance (2024)As Alberta Jackson | (Not seen) |
| Heart of Stone (2023)As King of Diamonds | (Not seen) |
| Swan Song (2021)As Dr. Eve Scott | (Not seen) |
| Four Good Days (2020)As Deb | (Not seen) |
| Hillbilly Elegy (2020)As Mamaw | (Not seen) |
| The Wife (2017)As Joan Castleman | (Not seen) |
| Crooked House (2017)As Lady Edith de Haviland | (Not seen) |
| Warcraft (2016) (AKA "Warcraft: The Beginning")As Alodi | (Not seen) |
| Guardians of the Galaxy (2014) (AKA "G.O.T.G.")As Nova Prime | (Not seen) |
| Hoodwinked Too! Hood vs. Evil (2011)As Granny (voice) | (Not seen) |
| Albert Nobbs (2011)As Albert Nobbs | (Not seen) |
| Evening (2007)As Mrs. Wittenborn | (Not seen) |
| The Chumscrubber (2005)As Carrie Johnson | (Not seen) |
| Hoodwinked! (2005) (AKA "Hoodwinked")As Granny (voice) | (Not seen) |
| The Stepford Wives (2004)As Claire Wellington | (Not seen) |
| The Lion in Winter (2003)As Eleanor of Aquitaine | (Not seen) |
| Le divorce (2003)As Olivia Pace | (Not seen) |
| Pinocchio (2002) (AKA "Roberto Benigni's Pinocchio") | (Not seen) |
| The Safety of Objects (2001)As Esther Gold | (Not seen) |
| Things You Can Tell Just by Looking at Her (2000)As Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca") | (Not seen) |
| 102 Dalmatians (2000)As Cruella de Vil | (Not seen) |
| Cookie's Fortune (1999)As Camille Dixon | (Not seen) |
| Tarzan (1999)As Kala (voice) | (Not seen) |
| In & Out (1997)As Herself | (Not seen) |
| Air Force One (1997) (AKA "AFO")As Vice President Kathryn Bennett | (Not seen) |
| 101 Dalmatians (1996)As Cruella De Vil | (Not seen) |
| Mary Reilly (1996)As Mrs. Farraday | (Not seen) |
| Mars Attacks! (1996)As First Lady Marsha Dale | (Not seen) |
| Serving in Silence: The Margarethe Cammermeyer Story (1995) (AKA "Serving in Silence")As Col. Margarethe Cammermeyer | (Not seen) |
| The House of the Spirits (1993)As Ferula Trueba | (Not seen) |
| Hook (1991)As Gutless | (Not seen) |
| Reversal of Fortune (1990)As Sunny von Bülow / Narrator | (Not seen) |
| Hamlet (1990)As Gertrude | (Not seen) |
| Dangerous Liaisons (1988)As Marquise Isabelle de Merteuil | (Not seen) |
| Fatal Attraction (1987) (AKA "Affairs of the Heart")As Alexandra "Alex" Forrest | (Not seen) |
| Jagged Edge (1985)As Teddy Barnes | (Not seen) |
| The Natural (1984)As Iris Gaines | (Not seen) |
| Greystoke: The Legend of Tarzan, Lord of the Apes (1984) | (Not seen) |
| The Big Chill (1983)As Sarah Cooper | (Not seen) |
| The World According to Garp (1982)As Jenny Fields | (Not seen) |