| Albert Brooks: Defending My Life (2023) | (Not seen) |
| Incredibles 2 (2018)As Helen Parr / Elastigirl (voice) | (Not seen) |
| Song to Song (2017) (AKA "Weightless")As Miranda | (Not seen) |
| The Big Sick (2017)As Beth Gardner | (Not seen) |
| Batman v Superman: Dawn of Justice (2016) (AKA "Batman Versus Superman: Dawn of Justice")As Senator Finch | (Not seen) |
| The Big White (2005)As Margaret Barnell | (Not seen) |
| Little Black Book (2004)As Barb | (Not seen) |
| The Incredibles (2004) (AKA "The Fantastics")As Helen Parr / Elastigirl (voice) | (Not seen) |
| Thirteen (2003)As Melanie 'Mel' Freeland | (Not seen) |
| Levity (2003)As Adele Easley | (Not seen) |
| Moonlight Mile (2002) (AKA "Baby's in Black")As Mona Camp | (Not seen) |
| Things You Can Tell Just by Looking at Her (2000)As Rebecca Waynon (segment "Fantasies About Rebecca") | (Not seen) |
| Timecode (2000)As Executive | (Not seen) |
| O Brother, Where Art Thou? (2000) (AKA "O' Brother")As Penny Wharvey-McGill | (Not seen) |
| Jesus' Son (1999)As Mira | (Not seen) |
| A Life Less Ordinary (1997)As O'Reilly | (Not seen) |
| Crash (1996)As Helen Remington | (Not seen) |
| Copycat (1995)As M.J. Monahan | (Not seen) |
| The Piano (1993) (AKA "Piano Lesson")As Ada McGrath | (Not seen) |
| The Firm (1993)As Tammy Hemphill | (Not seen) |
| Always (1989)As Dorinda Durston | (Not seen) |
| Broadcast News (1987)As Jane Craig | (Not seen) |
| Raising Arizona (1987)As Edwina "Ed" McDunnough | (Not seen) |
| Swing Shift (1984)As Jeannie Sherman | (Not seen) |
| Blood Simple. (1984) (AKA "Blood Simple")As Helene Trend (voice) (uncredited) | (Not seen) |
| The Burning (1981) (AKA "Cropsy")As Sophie | (Not seen) |