| Albert Brooks: Defending My Life (2023) | (Not seen) |
| Don't Look Up (2021)As President Orlean | (Not seen) |
| Little Women (2019)As Aunt Josephine March | (Not seen) |
| The Laundromat (2019)As Ellen Martin / Elena | (Not seen) |
| Mary Poppins Returns (2018)As Tatiana "Topsy" Topotrepolovsky | (Not seen) |
| Mamma Mia! Here We Go Again (2018)As Donna | (Not seen) |
| The Post (2017)As Kay Graham | (Not seen) |
| Suffragette (2015)As Emmeline Pankhurst | (Not seen) |
| Ricki and the Flash (2015)As Ricki Rendazzo | (Not seen) |
| The Homesman (2014)As Altha Carter | (Not seen) |
| Into the Woods (2014)As Witch | (Not seen) |
| The Giver (2014)As Chief Elder | (Not seen) |
| August: Osage County (2013)As Violet Weston | (Not seen) |
| The Iron Lady (2011)As Margaret Thatcher | (Not seen) |
| Julie & Julia (2009)As Julia Child | (Not seen) |
| It's Complicated (2009)As Jane Adler | (Not seen) |
| Fantastic Mr. Fox (2009)As Felicity Fox (voice) | (Not seen) |
| Doubt (2008)As Sister Aloysius Beauvier | (Not seen) |
| Mamma Mia! (2008) (AKA "Mamma Mia! The Movie")As Donna Sheridan | (Not seen) |
| Evening (2007)As Lila Ross | (Not seen) |
| Lions for Lambs (2007)As Janine Roth | (Not seen) |
| Rendition (2007)As Corrine Whitman | (Not seen) |
| The Ant Bully (2006)As Queen (voice) | (Not seen) |
| A Prairie Home Companion (2006)As Yolanda Johnson | (Not seen) |
| The Devil Wears Prada (2006)As Miranda Priestly | (Not seen) |
| Prime (2005)As Lisa Metzger | (Not seen) |
| Lemony Snicket's A Series of Unfortunate Events (2004)As Josephine Anwhistle | (Not seen) |
| The Manchurian Candidate (2004)As Senator Eleanor Prentiss Shaw (D-VA) | (Not seen) |
| Stuck on You (2003)As Self | (Not seen) |
| The Hours (2002)As Clarissa Vaughan | (Not seen) |
| Adaptation. (2002) (AKA "The Orchid Thief")As Susan Orlean | (Not seen) |
| A.I. Artificial Intelligence (2001) (AKA "A.I.")As Blue Mecha (voice) | (Not seen) |
| Music of the Heart (1999)As Roberta Guaspari | (Not seen) |
| Dancing at Lughnasa (1998)As Kate Mundy | (Not seen) |
| Before and After (1996)As Dr. Carolyn Ryan | (Not seen) |
| Marvin's Room (1996) (AKA "My Room")As Lee Wakefield Lacker | (Not seen) |
| The Bridges of Madison County (1995)As Francesca Johnson | (Not seen) |
| The River Wild (1994)As Gail Hartman | (Not seen) |
| The House of the Spirits (1993)As Clara del Valle Trueba | (Not seen) |
| Death Becomes Her (1992)As Madeline Ashton | (Not seen) |
| Postcards from the Edge (1990)As Suzanne Vale | (Not seen) |
| She-Devil (1989)As Mary Fisher | (Not seen) |
| A Cry in the Dark (1988) (AKA "Evil Angels")As Lindy Chamberlain | (Not seen) |
| Ironweed (1987)As Helen Archer | (Not seen) |
| Out of Africa (1985)As Karen Christence Dinesen Blixen | (Not seen) |
| Plenty (1985)As Susan Traherne | (Not seen) |
| Silkwood (1983)As Karen Silkwood | (Not seen) |
| Still of the Night (1982) (AKA "Stab")As Brooke Reynolds | (Not seen) |
| Sophie's Choice (1982)As Zofia "Sophie" Zawistowski | (Not seen) |
| The French Lieutenant's Woman (1981)As Sarah / Anna | (Not seen) |
| Kramer vs. Kramer (1979)As Joanna Kramer | (Not seen) |
| Manhattan (1979)As Jill | (Not seen) |
| The Deer Hunter (1978) (AKA "The Man Who Came to Play")As Linda | (Not seen) |
| Julia (1977)As Anne Marie | (Not seen) |