| The Room Next Door (2024) As Martha | (Not seen) |
| The Killer (2023) As The Expert | (Not seen) |
| Asteroid City (2023) As Dr. Hickenlooper | (Not seen) |
| Guillermo del Toro's Pinocchio (2022) As (voice) | (Not seen) |
| Three Thousand Years of Longing (2022) As Alithea Binnie | (Not seen) |
| The French Dispatch (2021) As J. K. L. Berensen | (Not seen) |
| The Dead Don't Die (2019) As Zelda Winston | (Not seen) |
| Uncut Gems (2019) As Anna (voice) | (Not seen) |
| Avengers: Endgame (2019) As The Ancient One | (Not seen) |
| Isle of Dogs (2018) As Oracle (voice) | (Not seen) |
| Okja (2017) As Lucy Mirando / Nancy Mirando | (Not seen) |
| War Machine (2017) As German Politician | (Not seen) |
| Doctor Strange (2016) As The Ancient One | (Not seen) |
| Hail, Caesar! (2016) (AKA "Hail, Caesar! A Tale of The Christ") As Thora Thacker / Thessaly Thacker | (Not seen) |
| Trainwreck (2015) As Dianna | (Not seen) |
| The Grand Budapest Hotel (2014) As Madame Céline Villeneuve Desgoffe-und-Taxis | (Not seen) |
| Only Lovers Left Alive (2013) As Eve | (Not seen) |
| The Zero Theorem (2013) As Dr. Shrink-Rom | (Not seen) |
| Snowpiercer (2013) As Minister Mason | (Not seen) |
| Moonrise Kingdom (2012) As Social Services | (Not seen) |
| We Need to Talk About Kevin (2011) As Eva Khatchadourian | (Not seen) |
| The Chronicles of Narnia: The Voyage of the Dawn Treader (2010) As The White Witch | (Not seen) |
| I Am Love (2009) (AKA "Io sono l'amore") As Emma Recchi | (Not seen) |
| The Limits of Control (2009) (AKA "No Limtis No Control") As Blonde | (Not seen) |
| The Curious Case of Benjamin Button (2008) As Elizabeth Abbott | (Not seen) |
| Burn After Reading (2008) As Katie Cox | (Not seen) |
| The Chronicles of Narnia: Prince Caspian (2008) (AKA "Prince Caspian") As White Witch | (Not seen) |
| Michael Clayton (2007) As Karen Crowder | (Not seen) |
| Broken Flowers (2005) As Penny | (Not seen) |
| Thumbsucker (2005) As Audrey Cobb | (Not seen) |
| The Chronicles of Narnia: The Lion, the Witch and the Wardrobe (2005) (AKA "The Chronicles of Narnia") As White Witch | (Not seen) |
| Constantine (2005) As Gabriel | (Not seen) |
| Young Adam (2003) As Ella Gault | (Not seen) |
| Adaptation. (2002) (AKA "The Orchid Thief") As Valerie Thomas | (Not seen) |
| Vanilla Sky (2001) As Rebecca Dearborn | (Not seen) |
| Possible Worlds (2000) As Joyce | (Not seen) |
| The Beach (2000) As Sal | (Not seen) |
| Wittgenstein (1993) As Lady Ottoline Morrell | (Not seen) |
| Orlando (1992) As Orlando | (Not seen) |
| The Garden (1990) As Madonna/Voice Overs | (Not seen) |
| War Requiem (1989) As The Nurse | (Not seen) |
| The Last of England (1988) As The Maid | (Not seen) |
| Caravaggio (1986) As Lena | (Not seen) |