| Albert Brooks: Defending My Life (2023)As Self | (Not seen) |
| Locked Down (2021)As Guy | (Not seen) |
| Hubie Halloween (2020)As Orderly Hal | (Not seen) |
| Beastie Boys Story (2020)As Himself | (Not seen) |
| The Meyerowitz Stories (2017) (AKA "The Meyerowitz Stories (New and Selected)")As Matthew Meyerowitz | (Not seen) |
| Zoolander 2 (2016) (AKA "2oolander")As Derek Zoolander | (Not seen) |
| While We're Young (2014)As Josh Schrebnick | (Not seen) |
| Night at the Museum: Secret of the Tomb (2014)As Larry Daley / Laaa | (Not seen) |
| The Secret Life of Walter Mitty (2013)As Walter Mitty | (Not seen) |
| Madagascar 3: Europe's Most Wanted (2012)As Alex (voice) | (Not seen) |
| The Watch (2012)As Evan | (Not seen) |
| Tower Heist (2011) (AKA "Penthouse")As Josh Kovacs | (Not seen) |
| Submarine (2010)As Soap Opera Star | (Not seen) |
| I'm Still Here (2010) (AKA "I'm Still Here: The Lost Years of Joaquin Phoenix")As Himself | (Not seen) |
| Little Fockers (2010)As Greg Focker | (Not seen) |
| Megamind (2010)As Bernard (voice) | (Not seen) |
| Greenberg (2010)As Roger Greenberg | (Not seen) |
| Night at the Museum: Battle of the Smithsonian (2009) (AKA "Night at the Museum 2")As Larry Daley | (Not seen) |
| August (2008) | (Not seen) |
| Tropic Thunder: Rain of Madness (2008)As Tugg Speedman | (Not seen) |
| Madagascar: Escape 2 Africa (2008) (AKA "Madagascar 2")As Alex (voice) | (Not seen) |
| Tropic Thunder (2008)As Tugg Speedman | (Not seen) |
| The Heartbreak Kid (2007) (AKA "Seven Day Itch")As Eddie Cantrow | (Not seen) |
| Awesome; I Fuckin' Shot That! (2006) (AKA "Awesome: I... Shot That!")As Himself | (Not seen) |
| School for Scoundrels (2006) (AKA "The Better Man")As Lonnie | (Not seen) |
| Night at the Museum (2006) (AKA "Night at the Museum: The IMAX Experience")As Larry Daley | (Not seen) |
| Tenacious D in The Pick of Destiny (2006) (AKA "Kings of Rock - Tenacious D")As Guitar Center Guy | (Not seen) |
| Madagascar (2005)As Alex (voice) | (Not seen) |
| Dodgeball: A True Underdog Story (2004) (AKA "Dodgeball")As White Goodman | (Not seen) |
| Anchorman: The Legend of Ron Burgundy (2004) (AKA "Action News")As Arturo Mendes | (Not seen) |
| Meet the Fockers (2004) (AKA "Meet the Fokkers")As Gaylord 'Greg' Focker | (Not seen) |
| Envy (2004)As Tim Dingman | (Not seen) |
| Starsky & Hutch (2004)As David Starsky | (Not seen) |
| Along Came Polly (2004) (AKA "Risk")As Reuben Feffer | (Not seen) |
| Pauly Shore Is Dead (2003)As Ben Stiller (uncredited) | (Not seen) |
| Duplex (2003) (AKA "Der Appartement-Schreck")As Alex Rose | (Not seen) |
| Orange County (2002)As Firefighter | (Not seen) |
| The Royal Tenenbaums (2001)As Chas Tenenbaum | (Not seen) |
| Zoolander (2001) (AKA "Derek Zoolander")As Derek Zoolander | (Not seen) |
| Meet the Parents (2000)As Gaylord "Greg" Focker | (Not seen) |
| Keeping the Faith (2000)As Rabbi Jake Schram | (Not seen) |
| Mystery Men (1999)As Mr. Furious | (Not seen) |
| Permanent Midnight (1998)As Jerry Stahl | (Not seen) |
| Your Friends & Neighbors (1998) (AKA "Friends and Neighbors")As Jerry | (Not seen) |
| Zero Effect (1998)As Steve Arlo | (Not seen) |
| There's Something About Mary (1998)As Ted Stroehmann | (Not seen) |
| Flirting with Disaster (1996)As Mel Coplin | (Not seen) |
| Happy Gilmore (1996) (AKA "Adam Sandler's Happy Gilmore")As Hal L. - Orderly in Nursing Home (uncredited) | (Not seen) |
| The Cable Guy (1996)As Sam Sweet / Stan Sweet | (Not seen) |
| Heavy Weights (1995) (AKA "Heavyweights")As Tony Perkis / Tony Perkis Sr. | (Not seen) |
| Reality Bites (1994)As Michael Grates | (Not seen) |
| Highway to Hell (1991)As Pluto's Cook / Attila the Hun | (Not seen) |
| Next of Kin (1989)As Lawrence Isabella | (Not seen) |
| Hot Pursuit (1987) (AKA "Persecucion intensa")As Chris Honeywell | (Not seen) |
| Empire of the Sun (1987)As Dainty | (Not seen) |