| Despicable Me 4 (2024)As Gru (voice) | (Not seen) |
| IF (2024)As Blue (voice) | (Not seen) |
| Asteroid City (2023)As Motel Manager | (Not seen) |
| Minions: The Rise of Gru (2022)As Gru (voice) | (Not seen) |
| Irresistible (2020)As Gary Zimmer | (Not seen) |
| Vice (2018)As Donald Rumsfeld | (Not seen) |
| Despicable Me 3 (2017)As Gru / Dru (voice) | (Not seen) |
| Cafe Society (2016) (AKA "Café Society")As Phil Stern | (Not seen) |
| The Big Short (2015)As Mark Baum | (Not seen) |
| Minions (2015)As Gru (voice) | (Not seen) |
| Alexander and the Terrible, Horrible, No Good, Very Bad Day (2014)As Ben Cooper | (Not seen) |
| Foxcatcher (2014) (AKA "Mark v. Du Pont: The True Story of a Shocking Murder")As John du Pont | (Not seen) |
| Anchorman 2: The Legend Continues (2013) (AKA "Anchorman 2")As Brick Tamland | (Not seen) |
| The Way Way Back (2013) (AKA "The Way, Way Back")As Trent Ramsey | (Not seen) |
| Despicable Me 2 (2013)As Gru (voice) | (Not seen) |
| The Incredible Burt Wonderstone (2013)As Burt Wonderstone | (Not seen) |
| Seeking a Friend for the End of the World (2012)As Dodge Petersen | (Not seen) |
| Crazy, Stupid, Love. (2011) (AKA "Love Again")As Cal Weaver | (Not seen) |
| Dinner for Schmucks (2010) (AKA "The Dinner")As Barry | (Not seen) |
| Despicable Me (2010)As Gru (voice) | (Not seen) |
| Date Night (2010)As Phil Foster | (Not seen) |
| Horton Hears a Who! (2008) (AKA "Dr. Seuss' Horton Hears a Who")As The Mayor of Whoville (voice) | (Not seen) |
| Get Smart (2008)As Maxwell Smart | (Not seen) |
| Dan in Real Life (2007)As Dan Burns | (Not seen) |
| Knocked Up (2007)As Himself (uncredited) | (Not seen) |
| Evan Almighty (2007) (AKA "Bruce Almighty 2")As Evan Baxter | (Not seen) |
| Over the Hedge (2006)As Hammy (voice) | (Not seen) |
| Little Miss Sunshine (2006)As Frank Ginsberg | (Not seen) |
| Bewitched (2005)As Uncle Arthur | (Not seen) |
| The 40 Year Old Virgin (2005) (AKA "The 40 Year-Old Virgin")As Andy Stitzer | (Not seen) |
| Wake Up, Ron Burgundy: The Lost Movie (2004) (AKA "Anchorman: Wake-Up Ron Burgundy")As Brick Tamland | (Not seen) |
| Melinda and Melinda (2004) (AKA "Melinda & Melinda")As Walt | (Not seen) |
| Anchorman: The Legend of Ron Burgundy (2004) (AKA "Action News")As Brick Tamland | (Not seen) |
| Bruce Almighty (2003)As Evan Baxter | (Not seen) |
| Homegrown (1998) (AKA "Wild Smokers")As Party Extra with Funny Pants (uncredited) | (Not seen) |
| Curly Sue (1991)As Tesio | (Not seen) |