| Lonely Planet (2024)As Katherine Loewe | (Not seen) |
| The Son (2022)As Kate | (Not seen) |
| Halftime (2022) (AKA "Jennifer Lopez: Halftime")As Self | (Not seen) |
| Jurassic World Dominion (2022)As Dr. Ellie Sattler | (Not seen) |
| Little Women (2019)As Margaret "Marmee" March | (Not seen) |
| Marriage Story (2019)As Nora Fanshaw | (Not seen) |
| Cold Pursuit (2019)As Grace Coxman | (Not seen) |
| Trial by Fire (2018)As Elizabeth Gilbert | (Not seen) |
| Downsizing (2017)As Laura Lonowski | (Not seen) |
| Star Wars: Episode VIII - The Last Jedi (2017) (AKA "Star Wars: The Last Jedi")As Vice Admiral Amilyn Holdo | (Not seen) |
| The Founder (2016)As Ethel Kroc | (Not seen) |
| Certain Women (2016)As Laura Wells | (Not seen) |
| 99 Homes (2014)As Lynn Nash | (Not seen) |
| Wild (2014)As Bobbi Grey | (Not seen) |
| The Fault in Our Stars (2014) (AKA "TFiOS")As Frannie Lancaster | (Not seen) |
| The Master (2012)As Helen | (Not seen) |
| Fight for Your Right Revisited (2011)As Cafe Patron | (Not seen) |
| Everything Must Go (2010)As Delilah | (Not seen) |
| Little Fockers (2010)As Prudence | (Not seen) |
| Tenderness (2009)As Teresa | (Not seen) |
| Recount (2008)As Katherine Harris | (Not seen) |
| More Things That Happened (2007)As Susan Blue | (Not seen) |
| Inland Empire (2006) (AKA "Inland Empire: A Woman in Trouble")As Nikki Grace / Susan Blue | (Not seen) |
| Lonely Hearts (2006) (AKA "Lonely Hearts Killers")As Rene | (Not seen) |
| Happy Endings (2005)As Pam | (Not seen) |
| Novocaine (2001)As Jean Noble | (Not seen) |
| Jurassic Park III (2001) (AKA "JP3")As Dr. Ellie Sattler | (Not seen) |
| I Am Sam (2001)As Randy Carpenter | (Not seen) |
| Dr. T and the Women (2000) (AKA "Dr. T & the Women")As Peggy | (Not seen) |
| Citizen Ruth (1996) (AKA "Precious")As Ruth Stoops | (Not seen) |
| A Perfect World (1993)As Sally Gerber | (Not seen) |
| Jurassic Park (1993) (AKA "JP")As Dr. Ellie Sattler | (Not seen) |
| Industrial Symphony No. 1: The Dream of the Brokenhearted (1990)As Heartbroken Woman | (Not seen) |
| Wild at Heart (1990) (AKA "David Lynch's Wild at Heart")As Lula Fortune | (Not seen) |
| Fat Man and Little Boy (1989)As Kathleen Robinson | (Not seen) |
| Haunted Summer (1988)As Claire Clairmont | (Not seen) |
| Blue Velvet (1986)As Sandy Williams | (Not seen) |
| Mask (1985) (AKA "Peter Bogdanovich's Mask")As Diana Adams | (Not seen) |
| Teachers (1984)As Diane | (Not seen) |
| Ladies and Gentlemen, the Fabulous Stains (1982)As Jessica McNeil | (Not seen) |
| Alice Doesn't Live Here Anymore (1974)As Girl Eating Ice Cream Cone (uncredited) | (Not seen) |
| White Lightning (1973)As Sharon Ann, Maggie's daughter | (Not seen) |