| Zeroville (2019)As Vikar | (Not seen) |
| Arctic Justice (2019) (AKA "Arctic Justice: Thunder Squad")As Lemmy (voice) | (Not seen) |
| The Ballad of Buster Scruggs (2018)As Cowboy (segment "Near Algodones") | (Not seen) |
| The Disaster Artist (2017)As Tommy Wiseau | (Not seen) |
| Alien: Covenant (2017)As Jacob Branson (uncredited) | (Not seen) |
| Why Him? (2016)As Laird Mayhew | (Not seen) |
| King Cobra (2016)As Joe Kerekes | (Not seen) |
| Sausage Party (2016) (AKA "Sausage Party 3D")As Druggie (voice) | (Not seen) |
| The Night Before (2015)As James | (Not seen) |
| Wild Horses (2015)As Ben Briggs | (Not seen) |
| True Story (2015)As Christian Longo | (Not seen) |
| The Interview (2014)As Dave Skylark | (Not seen) |
| Good People (2014)As Tom Reed | (Not seen) |
| Palo Alto (2013)As Mr. B | (Not seen) |
| Third Person (2013)As Rick | (Not seen) |
| Homefront (2013)As Gator | (Not seen) |
| This Is the End (2013)As Himself | (Not seen) |
| Lovelace (2013)As Hugh Hefner | (Not seen) |
| Oz the Great and Powerful (2013)As Oz | (Not seen) |
| Marina Abramovic: The Artist Is Present (2012) (AKA "Marina Abramović: The Artist Is Present")As Himself | (Not seen) |
| The Iceman (2012)As Marty Freeman | (Not seen) |
| Spring Breakers (2012)As Alien | (Not seen) |
| Rise of the Planet of the Apes (2011)As Will Rodman | (Not seen) |
| Your Highness (2011)As Fabious | (Not seen) |
| The Green Hornet (2011) (AKA "Green Hornet")As Danny Crystal Cleer | (Not seen) |
| Howl (2010)As Allen Ginsberg | (Not seen) |
| 127 Hours (2010)As Aron Ralston | (Not seen) |
| Date Night (2010)As Taste | (Not seen) |
| Camille (2008)As Silias | (Not seen) |
| Milk (2008)As Scott Smith | (Not seen) |
| Pineapple Express (2008)As Saul Silver | (Not seen) |
| An American Crime (2007)As Andy | (Not seen) |
| Finishing the Game: The Search for a New Bruce Lee (2007) (AKA "Finishing the Game")As Dean Silo | (Not seen) |
| The Hills with James Franco and Mila Kunis (2007)As Justin Bobby | (Not seen) |
| In the Valley of Elah (2007)As Sergeant Carnelli | (Not seen) |
| Interview (2007)As Boyfriend on Phone (voice) | (Not seen) |
| Knocked Up (2007)As Himself (uncredited) | (Not seen) |
| Spider-Man 3 (2007) (AKA "Spider-Man 3: The IMAX Experience")As Harry Osborn / New Goblin | (Not seen) |
| Tristan + Isolde (2006) (AKA "Tristan & Isolde")As Tristan | (Not seen) |
| The Holiday (2006)As Himself | (Not seen) |
| Flyboys (2006) (AKA "Fly Boys")As Blaine Rawlings | (Not seen) |
| Annapolis (2006)As Jake Huard | (Not seen) |
| The Wicker Man (2006) (AKA "Wicker Man - Ritual des Bosen")As Bar Guy #1 | (Not seen) |
| The Dead Girl (2006)As Derek | (Not seen) |
| The Great Raid (2005)As Captain Prince | (Not seen) |
| Spider-Man 2 (2004) (AKA "Spider-Man 2 Lives")As Harry Osborn | (Not seen) |
| The Company (2003)As Josh | (Not seen) |
| Deuces Wild (2002)As Tino | (Not seen) |
| Sonny (2002)As Sonny | (Not seen) |
| City by the Sea (2002) (AKA "Mark of a Murderer")As Joey | (Not seen) |
| Spider-Man (2002) (AKA "Spider-Man: The Motion Picture")As Harry Osborn | (Not seen) |
| James Dean (2001)As James Dean | (Not seen) |
| Mean People Suck (2001)As Casey | (Not seen) |
| Whatever It Takes (2000)As Chris Campbell | (Not seen) |
| Never Been Kissed (1999)As Jason | (Not seen) |